Consuming alcohol with Cefotax IV/IM does not cause any harmful side effects.
SAFE IF PRESCRIBED
Cefotax IV/IM is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Cefotax IV/IM is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Avoid prolonged use of Cefotax IV/IM, since it may have possible effects such as rash and diarrhea.
Cefotax IV/IM may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Cefotax IV/IM should be used with caution in patients with kidney disease. Dose adjustment of Cefotax IV/IM may be needed. Please consult your doctor. Regular monitoring of kidney function may be advised while you are taking this medicine.
SAFE IF PRESCRIBED
Cefotax IV/IM is safe to use in patients with liver disease. No dose adjustment of Cefotax IV/IM is recommended.
Cefotax IV/IM is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the brain, lungs, ear, urinary tract, skin and soft tissues, bones and joints, blood and heart. It is also used to prevent infections during surgery. Cefotax IV/IM fights and stops the growth of many types of bacteria. This helps to improve your symptoms and cure the underlying infection. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. Your doctor will decide the correct dose for you. You should use this medicine regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The most common side effects of this medicine include rash and diarrhoea. Some people may develop temporary redness or pain at the site of injection. These side effects are usually mild but let your doctor know if they bother you or last more than a few days. Before using it, you should tell your doctor if you are allergic to any antibiotics, and if you have any liver or kidney problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.
Uses of Cefotax IV/IM
- Bacterial infections
Side effects of Cefotax IV/IM
- Allergic reaction
- Injection site reaction
How to use Cefotax IV/IM
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Cefotax IV/IM works
Cefotax IV/IM is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
What if you forget to take Cefotax IV/IM?
If you miss a dose of Cefotax IV/IM, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
- Your doctor has prescribed Cefotax IV/IM to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
- Discontinue Cefotax IV/IM and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
- Avoid consuming alcohol while taking Cefotax IV/IM as it may cause increased side effects.
Pneumonia, Meningitis, Peritonitis, Pelvic inflammatory disease, Endometritis, Pelvic cellulitis, Gonorrhea, Skin and skin structure infections, Respiratory tract infections, Urinary tract infections, Bacteremia/Septicemia, Bone and/or joint infections
IV Preparation Intermittent injection: Reconstitute 1 or 2 g with 10 mL SWI Infusion: Reconstitute infusion bottles with 50 or 100 mL NS or D5W IM: Add 2 mL, 3 mL or 5 mL of sterile or bacteriostatic water for inj to a vial
Adult: Infections Caused by Susceptible Organisms Uncomplicated: 1 g IV or IM q12hr Moderate to severe: 1-2 g IV or IM q8hr More serious (bloodstream infection [septicemia]): 2 g IV q6-8hr Life-threatening: 2 g IV q4hr; not to exceed 12 g/day Surgical prophylaxis 1 g 30-90 mins before procedure. Gonorrhoea 0.5-1 g as a single dose.
Children: IV, IM 50–180 mg/kg/day q6–8h 200–225 mg/kg/day for meningitis q6h Neonates: The recommended dosage is 50 mg/kg/day in 2 to 4 divided doses. In severe infections 150-200 mg/kg/day in divided doses have been given.
Renal impairment: Severe: After an initial loading dose of 1 g, half the daily dose w/o changing the frequency.
Hypersensitivity to cephalosporins.
Mode of Action
Cefotaxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
History of penicillin allergy; colitis; impaired renal function; pregnancy, lactation. Lactation: Drug enters breast milk; use with caution
Colitis, Elevated blood urea nitrogen (BUN) and creatinine, Elevated hepatic transaminases, Fever. Pain at inj site; hypersensitivity reactions, rash, pruritus; diarrhoea, nausea, vomiting; candidiasis; eosinophilia, neutropenia, leucopenia, thrombocytopenia. Potentially Fatal: Anaphylactic reaction; nephrotoxicity.
Pregnancy Category Note
Pregnancy category: B Lactation: Drug enters breast milk; use with caution
Probenecid decreases cefotaxime elimination. Potentially Fatal: Nephrotoxicity with furosemide and aminoglycosides.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.