Cuts, Wounds, Severe burns, Post-operative wound dressing, Bed sores
Administration
Burns: The burn wound should be cleaned and cream applied over all the affected areas to a depth of 3-5mm. Where necessary, the cream should be re-applied to any area from which it has been removed by patient activity. In burns, cream should be re...
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Adult Dose
Topical/Cutaneous
Treatment and prophylaxis of infection in severe burns
Adult: Apply onto affected area 1-2 times/day.
Silver sulfadiazine cream is contraindicated in patients known to be hypersensitivity to silver sulphonamide or to other components of the preparation such as cetyl alcohol or propylene glycol. Because sulphonamide therapy is known to increase the po...
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Mode of Action
Silver sulfadiazine has broad antimicrobial activity; it is active against gram-positive and gram-negative bacteria as well as some yeasts and fungi. The silver salt acts mainly on the cell wall and membrane to disrupt its intergrity thus allowing it...
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Precaution
Silver sulfadiazine cream should be used with caution in the presence of significant hepatic or renal impairment or if the condition of porphyria is suspected. Caution of use is required in patients known to be sensitive to systemic sulphonamides and...
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Side Effect
The most common sides effects are allergic reactions including burning, itching and rashes; argyria reported following prolonged use. Transient leucopenia may occur in patients receiving silver sulfadiazine therapy.
Interaction
Potentiates antidiabetic effect of sulphonylureas. Not antagonised by PABA.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.