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ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
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Sefety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Amocal BZ 5/20.
CONSULT YOUR DOCTOR
Amocal BZ 5/20 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
SAFE IF PRESCRIBED
Amocal BZ 5/20 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Amocal BZ 5/20 may cause side effects which could affect your ability to drive. As it is advisable to exercise caution when driving with Amocal BZ 5/20.
CAUTION
Amocal BZ 5/20 should be used with caution in patients with kidney disease. Dose adjustment of Amocal BZ 5/20 may be needed. Please consult your doctor. Regular monitoring of blood pressure is recommended for better dose adjustment.
CAUTION
Amocal BZ 5/20 should be used with caution in patients with liver disease. Dose adjustment of Amocal BZ 5/20 may be needed. Please consult your doctor. Amocal BZ 5/20 is started at a lower dose in patients with liver disease and further increased slowly with careful monitoring.
Medical Overview
Introduction
Amocal BZ 5/20 is used to treat hypertension (high blood pressure). This is a combination of two medicines that controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke. You can take Amocal BZ 5/20 at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine. It may cause side effects like ankle swelling, headache, weakness, numbness of extremities, flushing (sense of warmth in the face, ears, neck, and trunk), and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment. Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.
Uses of Amocal BZ 5/20
  • Hypertension (high blood pressure)
Side effects of Amocal BZ 5/20
Common
  • Ankle swelling
  • Headache
  • Tiredness
  • Palpitations
  • Increased potassium level in blood
  • Sleepiness
  • Cough
  • Taste change
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Decreased blood pressure
  • Upset stomach
How to use Amocal BZ 5/20
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amocal BZ 5/20 may be taken with or without food, but it is better to take it at a fixed time.
How Amocal BZ 5/20 works
Amocal BZ 5/20 is a combination of two medicines: Amlodipine and benazepril which lower blood pressure effectively. It works by relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently.
Quick Tips
  • You have been prescribed Amocal BZ 5/20 for the treatment of high blood pressure.
  • Lowering blood pressure reduces chance of future heart attack & strokes.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position.
  • Do not take Amocal BZ 5/20 if you are pregnant or planning for pregnancy.
Brief Description
Indication
Oral Hypertension Adult: Amlodipine component: 2.5-10 mg once daily; benazepril component: 10-40 mg once daily. Titrate dose gradually according to response. Elderly: Initiate with 2.5 mg Amlodipine component once daily. Hepatic impairment: Initiate with 2.5 mg Amlodipine component once daily. Titrate combination slowly in severe hepatic impairment.
Administration
Additive effect when used with catecholamine depleting drugs; monitor for hypotension and/or marked bradycardia. If used with clonidine, clonidine withdrawal should occur a few days after withdrawal of the beta-blocker to prevent rebound hypertension; if replacing clonidine by beta-blocker, beta-blocker should be introduced only after clonidine administration has stopped for several days. Concurrent use with prostaglandin synthase inhibiting drugs (e.g. indomethacin) may reduce the hypotensive effects of beta-blockers.
Adult Dose
Discontinue as soon as possible when pregnancy is detected; affects renin-angiotensin system, causing oligohydramnios, which may result in fetal injury and/or death. Caution in elderly, renal or hepatic impairment, congestive heart failure, severe aortic stenosis, unilateral or bilateral renal artery stenosis, use during surgery or anaesthesia. Amlodipine+Benazepril can cause symptomatic hypotension, especially in patients with salt/volume depletion. ACE inhibitors (ACEi) have been associated with cholestatic jaundice and fulminant hepatic necrosis; discontinue treatment if patient develops jaundice/marked elevation of liver enzymes. Monitor renal function and serum potassium periodically. Angioedema of the face, extremities, lips, tongue, glottis, larynx and intestinal angioedema have been reported in ACEi-treated patients. As with all ACEi, may cause persistent dry cough. Lactation: Minimal amounts of benazepril enters milk, but excretion of amlodipine is not known; not recommended
Renal Dose
Amlodipine is a dihydropyridine calcium antagonist. It lowers BP by relaxing the coronary vascular smooth muscles and producing coronary vasodilation; through inhibition of transmembrane Ca ion influx into vascular smooth muscle and cardiac muscle. It is also a peripheral vascular vasodilator. Benazepril and its active metabolite benazeprilat inhibit ACE, which results in decreased plasma angiotensin II and thus leading to decreased aldosterone secretion.
Contraindication
Safety and efficacy in paediatric patients have not been established.
Mode of Action
May be taken with or without food.
Precaution
Hypertension
Side Effect
Renal impairment: Decrease dose if CrCl <30 mL/min, severe liver impairment, or coadministered with diuretic
Pregnancy Category Note
>10% Amlodipine Peripheral edema (2-15%),Pulmonary edema (7-15%) 1-10% Amlodipine Abdominal pain (1.6%),Dizziness (1.1-3.4%),Dyspepsia (1-2%),Fatigue (4.5%),Flushing (0.7-2.6%),Headache (7.3%),Male sexual dysfunction (1-2%),Muscle cramps (1-2%),Nausea (2.9%),Palpitation (0.7-4.5%),Rash (1-2%),Somnolence (1-2%),Weakness (1-2%) Benazepril ARF if renal artery stenosis Cough (1-10%),Dizziness (4%),Fatigue (2%),Headache (6%),Nausea (1%),Postural dizziness (2%),Serum creatinine increased (2%),Somnolence (2%) Potentially Fatal: Analphylactoid reactions, angioedema, Stevens-Johnson syndrome.
Interaction
Patients with history of angioedema; pregnancy, lactation.
ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.