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ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
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Sefety Advices
বাংলা
English
SAFE
Consuming alcohol with Acmecilin IV/IM 500 does not cause any harmful side effects.
SAFE IF PRESCRIBED
Acmecilin IV/IM 500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Acmecilin IV/IM 500 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
SAFE
Acmecilin IV/IM 500 does not usually affect your ability to drive.
CAUTION
Acmecilin IV/IM 500 should be used with caution in patients with kidney disease. Dose adjustment of Acmecilin IV/IM 500 may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Acmecilin IV/IM 500 in patients with liver disease. Please consult your doctor.
Medical Overview
Introduction
Acmecilin IV/IM 500 is a penicillin-type of antibiotic used to treat a variety of bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract (eg. pneumonia), urinary tract, skin and soft tissue, and typhoid fever. Acmecilin IV/IM 500 is also used to prevent infection of the heart valves (bacterial endocarditis) in people with pre-existing heart disease. It is a broad-spectrum antibiotic that fights and stops the growth of many types of bacteria. This medicine should be taken on an empty stomach. Use it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication. Before taking this medicine, inform your doctor if you are allergic to penicillin or any penicillin-type of medicine. Rash, vomiting, allergic reactions, nausea and diarrhea may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor's supervision.
Uses of Acmecilin IV/IM 500
  • Bacterial infections
Side effects of Acmecilin IV/IM 500
Common
  • Rash
  • Vomiting
  • Allergic reaction
  • Nausea
  • Diarrhea
How to use Acmecilin IV/IM 500
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Acmecilin IV/IM 500 is to be taken empty stomach.
How Acmecilin IV/IM 500 works
Acmecilin IV/IM 500 is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
Quick Tips
  • Acmecilin IV/IM 500 is used to treat infections caused by bacteria.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Taking probiotics along with Acmecilin IV/IM 500 may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
  • Stop taking this medicine and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Brief Description
Indication
Adult: PO Susceptible infections 0.25-0.5 g 6 hrly. Typhoid and paratyphoid fever 1-2 g 6 hrly. Duration: 2 wk (acute infections); 4-12 wk (carriers). Uncomplicated gonorrhoea W/ probenecid: 2 g as single dose. IV/IM: IV Intrapartum prophylaxis against group B streptococcal infections Initial, 2 g, then 1 g 4 hrly until delivery. Septicaemia 150-200 mg/kg/day. Start with IV admin for 3 days, then IM inj 3-4 hrly. Continue treatment for at least 48-72 hr after patient has become asymptomatic or when there is evidence of bacterial eradication. IV/IM Susceptible infections 250-500 mg 6 hrly. Meningitis 2-3 g 4-6 hrly, may start w/ IV admin, then continue w/ IM inj. Inj Supplement to systemic therapy For intrapleural/intraperitoneal/intra-articular admin: 500 mg/day.
Administration
May reduce the efficacy of OC. May alter INR while on warfarin and phenindione. May reduce the efficacy of oral typhoid vaccines. May reduce the excretion of methotrexate. Reduced excretion w/ probenecid and sulfinpyrazone, resulting to increased risk of toxicity. Allopurinol increases ampicillin-induced skin reactions. Reduced absorption w/ chloroquine. Bacteriostatic antibacterials (e.g. erythromycin, chloramphenicol, tetracycline) may interfere w/ the bactericidal action of ampicillin.
Adult Dose
Renal failure; patients with lymphatic leukaemia or HIV infections; pregnancy and lactation. Lactation: Excreted in breast milk, use caution
Renal Dose
Ampicillin exerts bactericidal action on both gm+ve and gm-ve organisms. Its spectrum includes gm+ve organisms eg, S pneumoniae and other Streptococci, L monocytogenes and gm-ve bacteria eg, M catarrhalis, N gonorrhoea, N meningitidis, E coli, P mirabilis, Salmonella, Shigella, and H influenzae. Ampicillin exerts its action by inhibiting the synthesis of bacterial cell wall.
Contraindication
Susceptible infections Child: PO: 50–100 mg/kg/day divided q6hr if <20 >20 kg 1–2 g/day divided q6hr IV/IM: Child: 50–200 mg/kg/day q6h 300–400 mg/kg/day endocarditis/meningitis q4–6h
Mode of Action
Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals. Reconstitution: IM: Add 1.5 mL water for inj to 500 mg vial contents. IV: Dissolve 500 mg in 10 mL water for inj.
Precaution
Bacterial infections, Endocarditis, Typhoid fever, Community-acquired pneumonia, Uncomplicated gonorrhea, Susceptible infections, Bacterial meningitis, Paratyphoid fever, Septicaemia, Intrapartum prophylaxis against group B streptococcal infections
Side Effect
Renal impairment: Patients undergoing haemodialysis should receive an additional dose after the session. CrCl (ml/min) <10 Dose reduction or increase in dose interval.
Pregnancy Category Note
GI upset, nausea, vomiting, diarrhoea; blood dyscrasias; urticaria, exfoliative dermatitis, rash; fever, seizures; interstitial nephritis. Potentially Fatal: Anaphylactic shock; pseudomembranous colitis; neuromuscular hypersensitivity; electrolyte imbalance.
Interaction
Hypersensitivity; infectious mononucleosis.
ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.