Xamic IV/IM may cause excessive drowsiness with alcohol.
SAFE IF PRESCRIBED
Xamic IV/IM is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Xamic IV/IM is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Xamic IV/IM does not usually affect your ability to drive.
Xamic IV/IM should be used with caution in patients with kidney disease. Dose adjustment of Xamic IV/IM may be needed. Please consult your doctor.
SAFE IF PRESCRIBED
Xamic IV/IM is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Xamic IV/IM may not be needed in these patients. Please consult your doctor.
Xamic IV/IM is used to treat bleeding. It helps to prevent or reduce bleeding in conditions like tooth removal, heavy periods, dysfunctional uterine bleeding, nosebleed and in any oral, prostate or bladder surgery. Xamic IV/IM is an anti-fibrinolytic. It works by preventing the breakdown of clots which leads to stoppage of bleeding. This medicine must be taken in the dose and duration as advised by the doctor. You should not take it if you have any known allergy from this medicine. The most common side effects may be injection site reactions such as tiredness, nasal congestion or pain in muscle, bone or joint. Inform your doctor if you have undergone any cardiac surgery or you are suffering from any kidney disease. This medicine is safe to use in pregnant or breastfeeding mothers. It is also safe to use in patients suffering from liver diseases. It is advised not to consume alcohol after taking this medicine as there can be excessive drowsiness.
Uses of Xamic IV/IM
Side effects of Xamic IV/IM
- Nasal congestion (stuffy nose)
- Musculoskeletal (bone, muscle or joint) pain
How to use Xamic IV/IM
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xamic IV/IM is to be taken with food.
How Xamic IV/IM works
Xamic IV/IM is an anti-fibrinolytic. It works by preventing the breakdown of blood clots to control excessive bleeding during periods, or after surgery.
What if you forget to take Xamic IV/IM?
If you miss a dose of Xamic IV/IM, skip it and continue with your normal schedule. Do not double the dose.
- Xamic IV/IM helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
- Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
- If taking for heavy periods, take it on the first day as taking it before or after will not have any benefit.
- Your doctor may monitor your vision regularly while you are taking this medicine.
- Inform your doctor if you have a history of kidney or liver disease.
- Inform your doctor if there is no improvement in your bleeding after using this medicine for three consecutive periods.
Haemorrhage, Hereditary angioedema
May be taken with or without food.
Oral Short-term management of haemorrhage Adult: 1-1.5 g or 15-25 mg/kg bid or tid. Management of hereditary angioedema Adult: 1-1.5 g bid or tid. Intravenous Short-term management of haemorrhage Adult: 0.5-1 g or 10 mg/kg tid or 25-50 mg/kg daily by continuous infusion.
Oral Short-term management of haemorrhage Child: 25 mg/kg bid or tid. Management of hereditary angioedema Child: 25 mg/kg bid or tid. Intravenous Short-term management of haemorrhage Child: 10 mg/kg bid or tid.
Renal impairment: Adjust dose based on serum creatinine concentration: 120-250 micromol/l: 15 mg/kg bid daily; 250-500 micromol/l: 15 mg/kg once daily; >500 micromol/l: 7.5 mg/kg once daily or 15 mg/kg once every 48 hr.
Severe renal failure, active intravascular clotting, thromboembolic disease, colour vision disorders, subarachnoid bleeding.
Mode of Action
Tranexamic acid is an antifibrinolytic agent that competitively inhibits breakdown of fibrin clots. It blocks binding of plasminogen and plasmin to fibrin, thereby preventing haemostatic plug dissolution.
Mild to moderate renal impairment, irregular menstrual bleeding, previous history of thromboembolic disease, haematuria. Monitor closely in disseminated intravascular coagulation. Monitor LFT and eye examination regularly during long-term use. Discontinue if disturbance in colour vision occurs. Avoid IV inj rate >1 ml/minute due to risk of hypotension. Pregnancy, lactation.
>10% Headache (50.4%),Nasal and sinus symptoms (25.4%),Back pain (20.7%),Abdominal pain (19.8%),Musculoskeletal pain (11.2%) 1-10% Arthralgia (6.9%),Muscle cramps and spasms (5.8%),Migraine (6%),Anemia (5.6%),Fatigue (5.2%) Frequency Not Defined Visual abnormalities,Hypotension (with rapid injection),Nausea,Vomiting,Diarrhea
Potentially Fatal: Increased risk of thrombus formation with estrogens, Factor IX complex concentrates or anti-inhibitor coagulant concentrates. Increased risk of fatal thrombotic complications with tretinoin in acute promyelocytic leukaemia.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.