It is unsafe to consume alcohol with Uniclor.
SAFE IF PRESCRIBED
Uniclor is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Uniclor is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Avoid prolonged use of Uniclor, since it may have possible effects such as rash and diarrhea.
CONSULT YOUR DOCTOR
It is not known whether Uniclor alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Uniclor should be used with caution in patients with kidney disease. Dose adjustment of Uniclor may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Uniclor in patients with liver disease. Please consult your doctor.
Uniclor is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (e.g. pneumonia), ear, throat, nasal sinus, urinary tract, skin, soft tissues, bones, and joints. It is also used to prevent infections during surgery. Uniclor may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back. It will not work for viral infections such as flu or the common cold. Using any antibiotic when you do not need it can make it less effective for future infections. The most common side effects of this medicine include rash, vomiting, nausea, diarrhea, and changes in liver function tests. These are usually mild but let your doctor know if they bother you or last more than a few days. Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Avoid consuming alcohol while taking this medicine as it may cause unpleasant side effects like nausea, vomiting, sweating, anxiety, and palpitations.
Uses of Uniclor
- Bacterial infections
Side effects of Uniclor
- Allergic reaction
- Injection site reaction
- Increased liver enzymes
How to use Uniclor
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Uniclor may be taken with or without food, but it is better to take it at a fixed time.
How Uniclor works
Uniclor is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
What if you forget to take Uniclor?
If you miss a dose of Uniclor, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
- Your doctor has prescribed Uniclor 375mg Tablet MR to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
- Discontinue Uniclor 375mg Tablet MR and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
- Take it with food to avoid an upset stomach.
- Avoid consuming alcohol while taking Uniclor 375mg Tablet MR as it may cause increased side effects.
Pneumonia, Meningitis, Peritonitis, Otitis media, Septicaemia, Biliary-tract infections, Urinary-tract infections, Skin and skin structure infections, Upper and lower respiratory tract infections, Pharyngitis, Tonsillitis
May be taken with or without food.
Oral Urinary tract infections, Upper and lower respiratory tract infections, Skin infections, Otitis media Adult: As monohydrate: 250-500 mg every 8 hr. Max: 4 g daily.
Oral Urinary tract infections, Upper and lower respiratory tract infections, Skin infections, Otitis media Child: PO 20–40 mg/kg/day, max 1 g/day q12h 1-5 yr: 125 mg tid, >5 yr: 250 mg tid. Suspension & Paediatric Drops: 1 month - 1 year 2.5 ml t.i.d. 0.625 ml t.i.d 1 year - 5 year 5 ml t.i.d. 1.25 ml t.i.d over 5 years 10 ml t.i.d 2.5 ml t.i.d
Renal Impairment CrCl: 10-50 mL/min: Half to full dose CrCl: <10 mL/min: Half dose
Known hypersensitivity to cephalosporins.
Mode of Action
Cefaclor binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. It has bactericidal activity against gm-ve bacteria including E. coli, S. pneumoniae, N. gonorrhoea, P. mirabilis and H. influenzae.
Severe renal impairment; history of allergy to penicillin; pregnancy, lactation. Lactation: enters breast milk; use with caution
1-10% Diarrhea (3%),Increased transaminases (3%),Eosinophilia (2%),Moniliasis (2%),Vaginitis (2%),Rash (maculopapular, erythematous, or morbiliform) (1-2%) <1% Stevens-Johnson syndrome,Pseudomembranous colitis,Nausea,Vomiting,Anemia,Neutropenia,Jaundice Potentially Fatal: Anaphylactic reaction; pseudomembranous colitis.
Pregnancy Category Note
Pregnancy No adequate and well-controlled studies in pregnant women Because animal reproduction studies are not always predictive of human response, cefaclor should be used during pregnancy only if necessary Lactation Effect on nursing infants is unknown; exercise caution when cefaclor is administered to a nursing woman Extended-release tablets No studies in lactating women performed; small amounts of cefaclor (?0.21 mcg/mL) detected in human milk following administration (single 500-mg dose of cefaclor extended-release tablets)
May enhance the nephrotoxic effect of aminoglycosides. May diminish the therapeutic effect of BCG, typhoid vaccine and Na picosulfate. Concomitant use w/ warfarin may increase prothrombin time. Probenecid inhibits renal excretion of cefaclor.
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.