It is not known whether it is safe to consume alcohol with Sofenib. Please consult your doctor.
CONSULT YOUR DOCTOR
Sofenib is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
UNSAFE
Sofenib is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
SAFE
Sofenib does not usually affect your ability to drive.
SAFE IF PRESCRIBED
Sofenib is safe to use in patients with kidney disease. No dose adjustment of Sofenib is recommended.
Regular monitoring of blood tests may be advised while you are taking this medicine.
CAUTION
Sofenib should be used with caution in patients with severe liver disease. Dose adjustment of Sofenib may be needed. Please consult your doctor.
Medicine Overview of Sofenib 200mg Tablet
Introduction
Sofenib belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.
Sofenib should be taken on an empty stomach, but try to have it at the same time every day to get ... Show more
Uses of Sofenib
Liver cancer
Kidney cancer
Thyroid cancer
Side effects of Sofenib
Common
Fatigue
Nausea
Loss of appetite
Diarrhea
Abdominal pain
Hair loss
Weight loss
Rash
Painful blisters on hands and feet
How to use Sofenib
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sofenib is to be taken empty stomach.
How Sofenib works
Sofenib is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
What if you forget to take Sofenib?
If you miss a dose of Sofenib, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
Sofenib is used in the treatment of liver, kidney, and thyroid cancer.
Take it without food, or with a low fat meal and a full glass of water.
Take it at the same time everyday to maintain consistent levels in your body.
Women who could get pregnant should use a reliable method of contraception to prevent pregnancy while taking this medicine.
Your doctor may regularly monitor your blood pressure while you are taking this medicine.
Inform your doctor if you get a skin rash, or any pain, swelling, and redness of your hands and feet while you are taking this medicine.
Do not change the dose or discontinue use without consulting your doctor.
Brief Description
Indication
Renal cell carcinoma, Hepatocellular Carcinoma, Thyroid Cancer
Administration
Should be taken on an empty stomach. Take on an empty stomach or w/ a low or moderate fat meal. If the patient intends to have a high fat meal, sorafe ... Show more
Adult Dose
Oral
Advanced renal cell carcinoma, Hepatocellular Carcinoma, Thyroid Cancer
Adult: 400 mg bid. May continue until patient is no longer responding o ... Show more
Child Dose
Safety and efficacy not established
Renal Dose
Renal Impairment
Mild to moderate: Dose adjustment not necessary
Severe renal impairment: Not studied
Contraindication
Hypersensitivity
Mode of Action
Sorafenib inhibits cell surface and intracellular kinases to reduce proliferation of tumour cells.
Precaution
Interrupt teatment if patient develops cardiac infarction, ischaemia and/or bleeding fatalities. Regular monitoring of BP, CBC and platelet is recomme ... Show more
Side Effect
>10%
Thrombocytopenia (12-46%),Anemia (44%),Diarrhea (43%),Rash/desquamation (40%),Fatigue (37%),Abd pain (31%),Hand-foot skin reaction (30%),Weight ... Show more
Interaction
Inducers of isoenzyme CYP3A4 e.g. carbamazepine, dexamethasone, phenobarbital, phenytoin, rifampicin may decrease sorafenib plasma concentration. Coad ... Show more
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.