Caution is advised when consuming alcohol with SB-Amlod. Please consult your doctor.
CONSULT YOUR DOCTOR
SB-Amlod may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
SB-Amlod is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SB-Amlod may cause side effects which could affect your ability to drive. SB-Amlod may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.
SAFE IF PRESCRIBED
SB-Amlod is safe to use in patients with kidney disease. No dose adjustment of SB-Amlod is recommended.
SB-Amlod should be used with caution in patients with liver disease. Dose adjustment of SB-Amlod may be needed. Please consult your doctor. SB-Amlod is started at a lower dose in patients with liver disease and further increased slowly with careful monitoring.
SB-Amlod belongs to a class of medicines known as a calcium channel blockers. It is used to treat high blood pressure (hypertension) and prevent angina (heart-related chest pain). It lowers blood pressure and reduces the workload of the heart which helps in preventing heart attacks and strokes. SB-Amlod may be prescribed alone or along with other medicines. The dose depends on what you are taking it for and the severity of your condition. You can take it at any time of the day, with or without food, but it is best to take it at the same time each day. You should take this medicine for as long as it is prescribed for you. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping youself active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine. The most common side effects include fatigue, swelling in the feet or ankles, sleepiness, dizziness, flushing, headache and unusual beating of the heart (palpitations). Consult your doctor if any of these side effects bother you or do not go away. Before taking it, let your doctor know if you have any liver, heart or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking, especially those used to treat high blood pressure or heart conditions. You should have your blood pressure checked regularly to make sure that this medicine is working properly.
Uses of SB-Amlod
- Hypertension (high blood pressure)
- Angina (heart-related chest pain)
Side effects of SB-Amlod
- Ankle swelling
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Edema (swelling)
- Abdominal pain
How to use SB-Amlod
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SB-Amlod may be taken with or without food, but it is better to take it at a fixed time.
How SB-Amlod works
SB-Amlod is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. In heart-related chest pain (angina), the enhanced blood flow in the body relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.
What if you forget to take SB-Amlod?
If you miss a dose of SB-Amlod, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
- Take it at the same time every day to help you remember to take it.
- A sudden drop in your blood pressure may occur, especially when you first start taking SB-Amlod. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
- It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how SB-Amlod affects you.
- Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding.
Oral Prinzmetal's angina; Stable angina Adult: Initially, 5 mg once daily increased to 10 mg once daily if necessary. Elderly: Initially, 2.5 mg once daily. maintenance: 10 mg/day Hepatic impairment: Initially, 2.5 mg once daily. Hypertension Adult: Initially, 5 mg once daily increased to 10 mg once daily if necessary. Elderly: Initially, 2.5 mg once daily. may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day PO; maintenance: 5-10 mg/day PO Hepatic impairment: Initially, 2.5 mg once daily.
Plasma concentrations may be elevated w/ CYP3A4 inhibitors (e.g. azole antifungals, ritonavir). Concomitant therapy w/ simvastatin may increase risk of myopathy including rhabdomyolysis. May increase ciclosporin plasma levels and conivaptan.
Impaired liver or renal function, CHF, sick-sinus syndrome, severe ventricular dysfunction, hypertrophic cardiomyopathy, severe aortic stenosis. Caution when used in patients with idiopathic hypertrophic subaortic stenosis. Elderly, children. Pregnancy, lactation. Use in renal failure: Although Amlodipine is excreted primarily via kidney, mild renal impairment does not appear to have an effect on the plasma concentrations. Severe renal impairment may however require a dosage reduction. Amlodipine is not dialyzable. Use in patients with impaired hepatic function: Amlodipine half-life is prolonged in patient with impaired hepatic function. Amlodipine should therefore be administered at lower (5mg) initial dose in these patients. Use in heart failure: An increased number of pulmonary oedema has been reported. Lactation: Unknown whether drug is excreted in milk; use not recommended
Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina.
Hypertension <6 years: Safety and efficacy not established >6 years: 2.5-5 mg/day PO
Mode of Action
May be taken with or without food.
Mild to moderate hypertension, Chronic stable and vasospastic angina, Raynaud's disease, Coronary Artery Disease, HTN, Stroke prevention
Pregnancy Category Note
>10% Edema (1.8-10.8%),Pulmonary edema (7-15%) 1-10% Headache (7.3%),Fatigue (4.5%),Palpitations (0.7-4.5%),Dizziness (1.1-3.4%),Nausea (2.9%),Flushing (0.7-2.6%),Abdominal pain (1.6%),Somnolence (1.4%),Male sexual disorder (1-2%),Drowsiness (1%),Pruritus (1-2%),Skin rash (1-2%),Muscle cramps (1-2%),Muscle weakness (1-2%) Potentially Fatal: Hypotension, bradycardia, conductive system delay and CCF.
Hypersensitivity to Amlodipine or other calcium channel antagonist, Severe hypertension.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.