It is unsafe to consume alcohol with Panagra.
CONSULT YOUR DOCTOR
Information regarding the use of Panagra during pregnancy is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Panagra during breastfeeding is not available. Please consult your doctor.
Panagra may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Panagra is safe to use in patients with kidney disease. No dose adjustment of Panagra is recommended. However, inform your doctor if you have any underlying kidney disease. A lowering of dose may be considered if it is not well-tolerated.
Panagra should be used with caution in patients with severe liver disease. Dose adjustment of Panagra may be needed. Please consult your doctor. There is limited information available on the use of Panagra in patients with severe liver disease.
Panagra is a prescription medicine used to treat erectile dysfunction (impotence) in men. It works by increasing blood flow to the penis. This helps men to get or maintain an erection. It belongs to a group of medicines known as phosphodiesterase type 5 (PDE 5) inhibitors. Panagra may be taken on an empty stomach or with a meal. It should be strictly taken as advised by your doctor. You should take it about 1 hour before you plan to have sex. The amount of time it takes to work varies from person to person, but it normally takes between 30 minutes and 1 hour. This medicine will only help you to get an erection if you are sexually stimulated. However, you should not take this medicine if you do not have erectile dysfunction. It should not be taken more than once a day. The most common side effects of this medicine are flushing (sense of warmth), headache, dizziness, blurred vision, muscle pain, stomach upset, and rash. Talk to your doctor if any of the side effects bother you or do not go away. This medicine is not intended for use by women and men should avoid using any other medicines to treat impotence without talking to a doctor first. It can be dangerous to take it along with medicines called nitrates (often given for chest pain or angina). Do not take this medicine if you have severe heart or liver problems, have recently had a stroke or heart attack or if you have low blood pressure. Let your doctor know if you suffer from these or any other health problems before taking it. You should not drive if this medicine makes you feel dizzy. Avoid drinking alcohol while taking this medicine as it increases the chances of side effects.
Uses of Panagra
- Erectile dysfunction
Side effects of Panagra
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Blurred vision
- Muscle pain
- Upset stomach
- Altered vision
How to use Panagra
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Panagra may be taken with or without food, but it is better to take it at a fixed time.
How Panagra works
Panagra is a phosphodiesterase-5 (PDE-5) inhibitor. It works by relaxing the blood vessels in your penis, thereby increasing blood flow into the penis on sexual stimulation. This helps you achieve and maintain a hard, erect penis suitable for sexual activity.
What if you forget to take Panagra?
If you miss a dose of Panagra, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
- You have been prescribed Panagra for the treatment of erectile dysfunction.
- It is best to take it an hour before sexual intercourse. But, you can take it anytime between 30 minutes and 4 hours before sexual activity.
- Do not take it more than once a day.
- Seek medical attention if the erection persists for more than 4 hours after sexual intercourse.
- Do not use Panagra if you have recently taken nitrates (medicines used in angina or chest pain).
- Do not take it if you have had a heart attack in the past 3 months, or stroke or heart failure in the past 6 months.
Erectile dysfunction, Pulmonary arterial hypertension
May be taken with or without food.
Oral Erectile dysfunction Adult: 50 mg about 1 hr before sexual intercourse. May adjust dose depending on penile response. Max: 100 mg/dose and not to be taken > once in 24 hr. Elderly: >65 yr: Lower initial dose at 25 mg. Hepatic impairment: Initially, 25 mg. Pulmonary Arterial Hypertension 20 mg 3 times daily, administered 4-6 hours apart
Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Initially, 25 mg.
Hypersensitivity. Patients concurrently or intermittently using organic nitrates in any form.
Mode of Action
Sildenafil inhibits phosphodiesterase type-5 (PDE5) which is responsible for cGMP degradation in the corpus cavernosum. Inhibition of PDE5 increases cGMP levels in the corpus cavernosum which results in smooth muscle relaxation and inflow of blood to the corpus cavernosum.
Caution when used in patients with anatomical deformation of penis or conditions that may predispose them to priapism (e.g. sickle cell anaemia, myeloma, or leukaemia). Mild, transient, dose-related impairment of colour discrimination (blue/green) may occur. Hepatic or severe renal impairment, bleeding disorders, active peptic ulceration, hypotension, recent history of stroke, MI, arrhythmias, unstable angina, heart failure or retinal disorders. May cause sudden loss or decrease in hearing.
>10% Headache (7-16%) 1-10% Flushing (4-10%),Epistaxis (8%),Dyspepsia (4-8%),Insomnia (6%),Erythema (5%),Diarrhea (4%),Dizziness (2%),Skin rash (2%)
Inhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the plasma concentrations of sildenafil. Symptomatic hypotension when used with beta-blockers. Plasma concentrations are increased by ritonavir. Potentially Fatal: May potentiate hypotensive effects of of organic nitrates and nicorandil.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.