Items
0
Delivery to
Bangladesh
All
Hello, User
Account & Orders
0
Shop By Category
Call for Order
Shop By Category
Loading...
ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
Register
0 People recently viewed this

Out of Stock
Currently unavailable, please request or choose another variant.
0.00
Notify
Select Quantity
0
Sefety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Oxaliplatin PhaRes. Please consult your doctor.
CONSULT YOUR DOCTOR
Oxaliplatin PhaRes is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
UNSAFE
Oxaliplatin PhaRes is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
UNSAFE
Oxaliplatin PhaRes may cause side effects which could affect your ability to drive. Oxaliplatin_name$ treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.
CAUTION
Oxaliplatin PhaRes should be used with caution in patients with severe kidney disease. Dose adjustment of Oxaliplatin PhaRes may be needed. Please consult your doctor. Limited information is available on the use of Oxaliplatin PhaRes in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
CAUTION
Oxaliplatin PhaRes should be used with caution in patients with liver disease. Dose adjustment of Oxaliplatin PhaRes may be needed. Please consult your doctor.
Medical Overview
Introduction
Oxaliplatin PhaRes is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Oxaliplatin PhaRes is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.
Uses of Oxaliplatin PhaRes
  • Cancer of colon and rectum
Side effects of Oxaliplatin PhaRes
Common
  • Nausea
  • Fatigue
  • Anemia (low number of red blood cells)
  • Vomiting
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Low blood platelets
  • Increased liver enzymes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomatitis (Inflammation of the mouth)
How to use Oxaliplatin PhaRes
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Oxaliplatin PhaRes works
Oxaliplatin PhaRes is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
What if you forget to take Oxaliplatin PhaRes?
If you miss a dose of Oxaliplatin PhaRes, please consult your doctor.
Quick Tips
  • Oxaliplatin PhaRes is given as an injection into veins under the supervision of a doctor.
Brief Description
Indication
Colorectal cancer, Colon cancer
Administration
IV Preparation Reconstitute by adding 10 mL (for 50 mg vial) or 20 mL (for 100 mg vial) of SWI or D5W. Dilute required amount of reconstituted solution in an infusion solution of 250-500 mL of D5W. Do NOT use NS or chloride-containing solutions Do not use aluminum-containing needles or IV administration sets that may come in contact with carboplatin (aluminum can react causing precipitate formation and loss of potency) IV Administration Flush infusion line with D5W prior to administration of oxaliplatin or any concomitant drug Use separate bags for oxaliplatin and leucovorin (administered through Y-site)
Adult Dose
Intravenous Advanced colorectal cancer Adult: Day 1: Oxaliplatin 85 mg/m² IV + leucovorin 200 mg/m² IV infused over 2 hr, THEN 5-FU 400 mg/m² IV bolus over 2-4 minutes, THEN 5-FU 600 mg/m² IV infusion in D5W (500 mL) over 22 hr Day 2: Same regimen WITHOUT oxaliplatin Repeat every 2 weeks Adjuvant therapy in stage III colon cancer Adult: Day 1: Oxaliplatin 85 mg/m² IV + leucovorin 200 mg/m² IV infused over 2 hr, THEN 5-FU 400 mg/m² IV bolus over 2-4 minutes, THEN 5-FU 600 mg/m² IV infusion in D5W (500 mL) over 22 hr Day 2: Same regimen WITHOUT oxaliplatin Every 2 wk; given for 12 cycles, for a total of 6 months Dose Modification If persistent Grade 2 neuropathy, decrease dose to 75 mg/m² If persistent Grade 3 neuropathy, consider discontinuing oxaliplatin After recovery from grade 3/4 GI or grade 3/4 hematological toxicity: Decrease dose to 75 mg/m² , AND decrease 5-FU by 20% (300 mg/m² bolus, 500 mg/m² infusion)
Child Dose
Safety and efficacy not established
Renal Dose
Renal Impairment Exposure of unbound platinum tends to increase in renally impaired patients Mild (CrCl 50-80 mL/min): No dosage adjustment required Moderate (CrCl 30-49 mL/min): No dosage adjustment required Severe (CrCl <30 mL/min): Reduce starting dose
Contraindication
Pregnancy. Peripheral neuropathy with functional impairment. Severe renal impairment.
Mode of Action
Oxaliplatin, a platinum-containing complex similar to cisplatin, is an alkylating agent. After intracellular hydrolysis, the platinum compound binds to DNA forming cross-links which inhibit DNA replication and transcription, resulting in cell death.
Precaution
Should be administered under the supervision of an experienced cancer chemotherapy physician. Use appropriate precautions for handling and disposal. Monitor neurological status and dose should be reduced if symptoms are prolonged or severe. Monitor blood counts during treatment and courses should not be repeated until blood counts have recovered. Caution in elderly, moderate degrees of renal impairment. Avoid using aluminum-containing needles or IV admin sets that may come into contact with oxaliplatin as aluminum has been reported to cause degradation of platinum compounds. Lactation. Lactation: not known if excreted in milk
Side Effect
>10% Peripheral neuropathy (76%),Anemia (64%),Nausea (64%),Fatigue (61%),Diarrhea (46%),Vomiting (37%),Abdominal pain (31%),Constipation (31%),Thrombocytopenia (30%),Fever (25%),Anorexia (20%),Leukopenia (13%),Dyspnea (13%),Cough (11%) 1-10% Edema (10%),Neutropenia (7%),Pharyngolaryngeal dysesthesia (1-2%) <1% Pulmonary fibrosis,Posterior leukoencephalopathy syndrome Frequency Not Defined Anaphylactic-like reaction (uncommon),Pulmonary fibrosis (uncommon) Potentially Fatal: Anaphylaxis, pulmonary fibrosis.
Interaction
May decrease plasma levels of digoxin. May increase risk of toxicity with nephrotoxic drugs. When administered as sequential infusions, taxane derivatives (docetaxel, paclitaxel) should be administered before oxaliplatin to limit myelosuppression and enhance efficacy.
ফার্মেসীর জন্য পাইকারি দামে ঔষধ কিনতে রেজিস্টেশন করুন
Register
0 People recently viewed this

Out of Stock
Currently unavailable, please request or choose another variant.
0.00
Notify
Select Quantity
0
Additional Offers
Cashback
৳100
For purchasing above ৳5000+
Cashback
৳80
For purchasing above ৳4000+
Cashback
৳60
For purchasing above ৳3000+
Cashback
৳40
For purchasing above ৳2000+
Cashback
৳20
For purchasing above ৳1000+
Similar Products
see all
LoadingLoadingLoadingLoadingLoadingLoading
More from ZAS Corporation
see all
LoadingLoadingLoadingLoadingLoadingLoading
Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.